Endocrine Abstracts

Stress hyperglycaemia is a widely recognised feature of critical illness. Spontaneous hypoglycaemia, by contrast, is an underappreciated but serious complication. Here I present three cases encountered over 12 months in a single teaching hospital.Case 1: 59 year old female. Admitted with fever and leg pain. Cellulitis diagnosed and antibiotics commenced. Hours later, she became unresponsive and shocked, with evident necrotisi...

Stress hyperglycaemia is a widely recognised feature of critical illness. Spontaneous hypoglycaemia, by contrast, is an underappreciated but serious complication. Here I present three cases encountered over 12 months in a single teaching hospital.Case 1: 59 year old female. Admitted with fever and leg pain. Cellulitis diagnosed and antibiotics commenced. Hours later, she became unresponsive and shocked, with evident necrotisi...

Bladder Paragangliomas (PGLs) are a rare manifestation of sympathetic chain PGLs and occur in prone patients with SDH mutation.They often display an aggressive phenotype with metastatic disease and require long-term follow up. SDHB immunostaining plays a significant role in initial risk stratification and facilitating appropriate genetic testing. We report four cases illustrating diagnostic management and outcome issues in this rare neuroendocrine pathology; two with SDHB muta...

Bladder Paragangliomas (PGLs) constitute < 1% of all bladder tumours and 5% in our patient cohort of 80 patients with tumours due to SDH deficiency. They often display an aggressive phenotype with metastatic disease and require long-term follow up. SDHB immunostaining plays a significant role in initial risk stratification and facilitating appropriate genetic testing. We present four cases of bladder PGLs; two with SDHB mutation, one SDHA and one is awaiting extended genet...

Bladder Paragangliomas (PGLs) constitute < 1% of all bladder tumours and 5% in our patient cohort of 80 patients with tumours due to SDH deficiency. They often display an aggressive phenotype with metastatic disease and require long-term follow up. SDHB immunostaining plays a significant role in initial risk stratification and facilitating appropriate genetic testing. We present four cases of bladder PGLs; two with SDHB mutation, one SDHA and one is awaiting extended genet...